Cell division requires the coordinated action of proteins that promote actomyosin contraction, membrane trafficking, and extracellular matrix remodeling. Wloka et al. reveal that, in budding yeast, the type II myosin Myo1 acts as an immobile scaffold at the bud neck to organize proteins involved in forming the primary septum during cytokinesis.
Download our Journal Club pack to aid your discussion of Wloka et al.'s study and its implications for cell division in both budding yeast and higher organisms. The pack includes a complete pdf of the paper, a PowerPoint file of Wloka et al.’s figures, supplemental videos, and the latest biosights video podcast, which features an interview with the study’s senior author, Erfei Bi (University of Pennsylvania, Philadelphia).