Rapid wound repair is generally thought to be initiated by intrinsic cues, such as changes in the structure or mechanics of damaged tissues. Gault et al. reveal that an extrinsic signal – the osmolarity of the external environment – can stimulate wound closure in zebrafish by inducing epithelial cell migration.
Download our Journal Club pack to aid your discussion of Gault et al.'s study and its implications for wound repair. The pack includes a complete pdf of the paper, a PowerPoint file of Gault et al.’s figures, supplemental videos, and the latest biosights video podcast, which features an interview with the paper’s senior author, Philipp Niethammer (Memorial Sloan Kettering Cancer Center, New York).