During mitosis, numerous proteins accumulate around the mitotic spindle to help it assemble and segregate sister chromatids correctly. Schweizer et al. reveal that a membranous spindle envelope facilitates the accumulation of these proteins by excluding large organelles from the spindle region.
Download our Journal Club pack to aid your discussion of Schweizer et al.'s study and its implications for spindle assembly and function. The pack includes a complete pdf of the paper, a PowerPoint file of Schweizer et al.'s figures, supplemental videos, and the latest biosights video podcast, which features an interview with the paper's senior author, Helder Maiato (University of Porto, Porto, Portugal).